解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::To increase the number of type I loci on the chicken linkage map, chicken genes containing microsatellite sequences (TAn, CAn, GAn, An) were selected from the nucleotide sequence database and primers were developed to amplify the repeats. Initially, 40 different microsatellites located within genes were tested on a pa...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1046/j.1365-2052.1999.00527.x
更新日期:1999-12-01 00:00:00
abstract::It is important for bovine DNA testing laboratories to provide the cattle industry with accurate estimates of the efficacy and reliability of DNA tests offered so that end users of this technology can adequately assess the cost-benefits of testing. To address these issues for bovine paternity testing, paternity exclus...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1046/j.1365-2052.1999.00511.x
更新日期:1999-10-01 00:00:00
abstract::Forty-two microsatellite loci were analysed in 23 highly inbred chicken lines derived from Leghorn, Jungle Fowl, Fayoumi and Spanish breeds. Line-specific alleles among breeds and lines were detected. The band-sharing (BS) values were calculated and the proportion of shared alleles distances (Dps) were estimated. The ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1046/j.1365-2052.1999.00505.x
更新日期:1999-08-01 00:00:00
abstract::Recently, linkage of a DNA microsatellite marker to inherited copper toxicosis has been reported in American Bedlington terrier families. Due to the fact that there is little exchange of breeding stock between the USA and Europe, it remains to be investigated whether in Europe the marker is informative and is linked w...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1046/j.1365-2052.1999.00451.x
更新日期:1999-06-01 00:00:00
abstract::Historical records suggest that horses inhabiting the island of Cheju in Korea are descendants of Mongolian horses introduced in 1276. Other studies, however, suggest that horses may have been present on the island prior to the Mongolian introduction. To determine the origin of the Cheju horses we used a phylogenetic ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1046/j.1365-2052.1999.00419.x
更新日期:1999-04-01 00:00:00
abstract::The amplified fragment length polymorphism (AFLP) technique has been used to enhance marker density in the East Lansing reference chicken genome map, using a backcross family derived from a Red Jungle Fowl by White Leghorn mating with White Leghorn as the recurrent parent. To date, 204 AFLP markers have been added, ex...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1046/j.1365-2052.1999.00411.x
更新日期:1999-02-01 00:00:00
abstract::The gene coding for the mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M), a pivotal component in gluconeogenesis from lactate via the Cori cycle, was highly polymorphic in strains of egg-type chickens (White Leghorn) of different origins. Based on MspI restriction fragment polymorphisms a total of seven allel...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1046/j.1365-2052.1998.295362.x
更新日期:1998-10-01 00:00:00
abstract::We tested 174 bovine microsatellite primer pairs for use in a primitive breed of sheep and two species of deer. Of 173 markers, 127 (73.4%) gave a product in Soay sheep (Ovis aries) of which 54 (42.5%) were polymorphic. One hundred and twenty-nine of 174 (74.1%) markers gave a product in red deer (Cervus elaphus) of w...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1046/j.1365-2052.1998.00347.x
更新日期:1998-08-01 00:00:00
abstract::Three polymorphisms were identified in a 1.6-kb fragment of the porcine calpastatin (CAST) gene and these polymorphisms were used for genetic linkage mapping. Linkage analysis revealed significant linkage of CAST to five microsatellites previously mapped to porcine chromosome 2; these microsatellites were S0010, S0226...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1046/j.1365-2052.1998.00319.x
更新日期:1998-06-01 00:00:00
abstract::As part of a whole genome scan undertaken to detect quantitative trait loci (QTL) affecting milk yield and composition, we have genotyped a granddaughter design comprising 1152 sons for six microsatellite markers spanning bovine chromosome 20. An analysis performed across families provided strong evidence (experiment-...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1046/j.1365-2052.1998.00307.x
更新日期:1998-04-01 00:00:00
abstract::The ovine NRAMP1 and cervine NRAMP1 cDNAs were cloned by RT PCR of RNA derived from macrophage enriched leukocyte preparations. The complete coding and 3' regions were sequenced. Both sheep and deer NRAMP1 proteins are 548 amino acids long. There are 77 and 73 amino acid differences, respectively, compared to the mous...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1046/j.1365-2052.1998.00224.x
更新日期:1998-02-01 00:00:00
abstract::The present report describes the isolation and genetic characterization of the porcine apolipoprotein E (apo-E) gene. A single positive recombinant phage clone containing a 10.7-kb insert was isolated from a porcine genomic library, and a 4.2-kb fragment was subcloned and sequenced. The 4.2-kb fragment contained the e...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1046/j.1365-2052.1998.00273.x
更新日期:1998-02-01 00:00:00
abstract::Genetic diversity in the second domain exon of Atlantic salmon (Salmo salar) major histocompatibility complex (Mhc) class I was investigated in two dams and nine of their haploid offspring by means of polymerase chain reaction (PCR) and DNA sequence analysis. A similar study was also performed on nine diploid offsprin...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1997.00183.x
更新日期:1997-12-01 00:00:00
abstract::A bovine yeast artificial chromosome (YAC) clone containing the superoxide dismutase 1 (SOD1) gene was used as a template for polymerase chain reaction (PCR) amplification using a conserved short interspersed nuclear element (SINE) primer. Two highly polymorphic microsatellites with nine and eight alleles were isolate...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1997.00158.x
更新日期:1997-10-01 00:00:00
abstract::A parallel testing of 4803 routine Quarter Horse parentage cases, using 15 loci of blood group and protein polymorphisms (blood typing) and 11 loci of dinucleotide repeat microsatellites (DNA typing), validated DNA markers for horse pedigree verification. For the 26 loci, taken together, the theoretical effectiveness ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1997.00123.x
更新日期:1997-08-01 00:00:00
abstract::The role of the porcine GH gene was investigated in 292 F2 animals of mating Wild Boar x Piétrain and in 310 F2 animals of mating Meishan x Piétrain. Forty-three traits of fattening, carcass composition, meat quality and stress resistance were recorded. For the analysis of associations between GH gene variants and qua...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1997.00093.x
更新日期:1997-04-01 00:00:00
abstract::Dexter cattle carry a genetic defect causing a dwarf phenotype in the heterozygotes (Dx+/-), while homozygotes (Dx+/+) are stillborn with extreme shortening of limbs and gross craniofacial defects and are described as 'bulldog' calves. The heterozygous phenotype has been likened to achondroplastic dwarfism in humans (...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1997.00068.x
更新日期:1997-02-01 00:00:00
abstract::Southern hybridization analysis of the ovine major histocompatibility complex (MHC) (MhcOvar) class II region, using sheep-specific probes for the DQA1, DQA2, DQB and DRA loci, has revealed extensive polymorphism. DQA1 and DQA2 had eight and 16 alleles respectively, DQB had six and DRA had three alleles. Little inform...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1996.tb00974.x
更新日期:1996-10-01 00:00:00
abstract::The mitochondrial DNA sequence of cytochrome b gene in a Thoroughbred horse was determined. By comparing DNA sequences between the Thoroughbred and published sequence data (two horses and one Grevyi zebra), polymerase chain reaction (PCR) primers were designed for amplification of a 590 bp DNA fragment in the cytochro...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1996.tb00979.x
更新日期:1996-10-01 00:00:00
abstract::Marker-assisted selection (MAS) uses genetic marker genotypes to predict an animal's production potential and will provide additional selection information for progeny testing. With the discovery of highly polymorphic microsatellite markers, the tools now exist to begin the search for economic trait loci (ETL), which ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1996.tb00484.x
更新日期:1996-08-01 00:00:00
abstract::An alloimmune reagent has been produced that distinguishes the equine factor Df in the D phenogroup, cfmqr, from that occurring in cefmqr and dfklr. Using this reagent it has been possible to correctly genotype Dc, d, f, k, l, m, q and r positive cells without recourse to family data. ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1996.tb00476.x
更新日期:1996-04-01 00:00:00
abstract::Three genomic clones were isolated from a size-selected pig DNA library by hybridization with a DNA-fingerprint probe. Analysis at the sequence level revealed that all three clones contain interrupted stretches of triplet repeats mainly composed of CAC and CAT triplets. Evaluation of the corresponding loci for polymor...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1995.tb02667.x
更新日期:1995-10-01 00:00:00
abstract::Three electrophoretic variants of erythrocyte malic enzyme (ME) in goats were reported. Inheritance data indicate that they are controlled by codominant alleles. The allele frequencies in four Mediterranean populations are given. ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1995.tb03255.x
更新日期:1995-08-01 00:00:00
abstract::Nucleotide sequence analysis of polymerase chain reaction products confirmed that ev21 integrated into one of two large homologous elements on the Z chromosome of late-feathering (LF) White Leghorn chickens. Southern blots of NotI-, NaeI-, KspI- and BamHI-digested DNA from early-feathering (EF) and LF White Leghorns, ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1995.tb03153.x
更新日期:1995-06-01 00:00:00
abstract::Two new alleles (A and E) of the bovine MUC locus which encodes PAS-1 protein, a glycoprotein of the milk fat globule membrane, are reported. The A allele was found in Italian Brown while E was present in the Jersey and the Piedmont breeds. ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1995.tb03163.x
更新日期:1995-06-01 00:00:00
abstract::Using agarose gel isoelectric focusing and immunoblotting with rabbit anti-rabbit C6, a genetic polymorphism was found in the sixth component of complement (C6) in 18 Asian native breeds or populations and three European breeds of dog. The C6 locus was highly polymorphic. The phenotype distribution data indicated that...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1995.tb02641.x
更新日期:1995-04-01 00:00:00
abstract::Microsatellite polymorphisms are finding increasing use in genetics. In addition to the random isolation of microsatellite markers, such markers can also be developed from sequences already present in public domain databases. An advantage of public domain databases is that these microsatellites are known to be located...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1995.tb02636.x
更新日期:1995-04-01 00:00:00
abstract::Four new alleles at the rabbit (Oryctolagus cuniculus) mannose-6-phosphate isomerase (E.C. 5.3.1.8, MPI) locus are proposed to account for phenotypes observed after starch gel electrophoresis and enzymatic staining of red cell lysates and tissues. Population data from various wild and domestic rabbit populations are p...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1995.tb02617.x
更新日期:1995-02-01 00:00:00
abstract::Primer sequences flanking 13 microsatellite loci isolated from the domestic horse (E. caballus) were successfully used to amplify homologous loci in the Przewalski's horse (E. przewalskii). The results demonstrate that the level of polymorphism at all 13 loci in the Przewalski's horse was comparable to that in the dom...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1994.tb00530.x
更新日期:1994-12-01 00:00:00
abstract::A well-established and characterized somatic cell hybrid panel was used to map three polymorphic microsatellites. Microsatellite S0072, representing the linkage group S0007-S0072, was assigned to porcine chromosome 14. Microsatellite S0009, representing the unassigned linkage group EAM-S0009-S0071, was assigned tentat...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1994.tb00369.x
更新日期:1994-10-01 00:00:00
abstract::A map of the ovine MHC class II DQ subregion has been constructed from overlapping cosmid clones. This region consists of two loci linked on a linear tract of 130 kb DNA. Each locus consists of a DQA and a DQB gene in a tail-to-tail orientation. The genes in each locus are transcribed but only those designated DQ1 exp...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1994.tb00200.x
更新日期:1994-08-01 00:00:00
abstract::Internationally recognized allo-antisera in lymphocyte microcytotoxicity assays are thought to detect allelic products of a single highly polymorphic class I locus. A recent report suggested that two bovine lymphocyte antigen (BoLA) class I loci are expressed at the protein level. However, 1D-IEF analysis of BoLA clas...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1994.tb00105.x
更新日期:1994-06-01 00:00:00
abstract::Using frequencies of 86 genes from 23 loci of blood group systems, blood and milk proteins, the genetic relationships among 14 cattle breeds including four native Balkan and four synthetic Balkan-Alp breeds were studied. The dendrogram and nonlinear map construction shows a consensus 'Balkan breed cluster', an 'Alp br...
journal_title:Animal genetics
pub_type: 历史文章,杂志文章
doi:10.1111/j.1365-2052.1994.tb00399.x
更新日期:1994-06-01 00:00:00
abstract::Polymerase chain reaction (PCR) primers specific to exon 2 of the bovine lymphocyte antigen (BoLA)-DRB3 gene were successfully used to amplify the equivalent region in 469 American bison (Bison bison). In domestic cattle, alleles of DRB3 are assigned through a restriction fragment length polymorphism (RFLP) analysis o...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1994.tb00409.x
更新日期:1994-06-01 00:00:00
abstract::A total of 419 individuals of four breeds with differing fecundity (Rhoenschaf, Merinolandschaf, East Friesian Milksheep, Romanov) and several wild sheep of the Ovis musimon, O. orientalis, O. vignei and O. ammon groups were screened for genetic variation at the beta A-inhibin (INHBA) locus with up to 11 enzymes. The ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:
更新日期:1994-02-01 00:00:00
abstract::Specific alloprecipitins were found in blood plasma of pigs, immunized by sera of Lpr1 positive donors. These precipitins detected a new allotype of the lipoprotein Lpr system which was designated Lpr3. Genetic studies confirmed its codominant inheritance and subgroup character. This linear subgroup of allotype Lpr1 i...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1993.tb00361.x
更新日期:1993-12-01 00:00:00
abstract::Major histocompatibility complex (MHC) class IV haplotypes were identified in a population of meat-type chickens by restriction fragment length polymorphism (RFLP) analysis. Fourteen different haplotypes were designated on the basis of restriction patterns obtained from Southern blots of PvuII- or BglII-digested DNA, ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1993.tb00339.x
更新日期:1993-10-01 00:00:00
abstract::Genomic DNA, prepared from 12 animals from four sheep flocks, was digested with either HaeIII or HinfI and probed with three DNA fingerprinting probes. Mean DNA fingerprint band sharing and band frequency calculated for each flock were used to estimate genetic diversity. Each of the DNA fingerprinting systems showed t...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1993.tb00345.x
更新日期:1993-10-01 00:00:00
abstract::Polymorphic bands were detected within the DQB and DRB regions of the ovine major histocompatibility complex by probing TaqI digested DNA from three large sheep half-sib families derived from a highly resistant ram. All animals were phenotypically assessed for Haemonchus contortus resistance by faecal egg counts and a...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1993.tb00311.x
更新日期:1993-08-01 00:00:00
abstract::Sorted chromosomes from each of the 20 clusters of the male porcine bivariate flow karyotype were amplified and biotinylated using DOP-PCR. The chromosomes comprising each cluster were identified by fluorescence in situ hybridization (FISH) of the 20 probes to R-banded male pig metaphase spreads. A standard flow karyo...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1993.tb00309.x
更新日期:1993-08-01 00:00:00